Not sure which routine is right for you? Send us an email at

Meet with a skin expert virtually to get personalized recommendations.

Book Your Consult →

Get treatment at our acclaimed dermatology clinic in Calgary.

About the Clinic →

Best Antioxidant Serums 2023 – Expert Advice Based on Skin Type

Best Antioxidant Serums 2023 – Expert Advice Based on Skin Type

Best Antioxidant Serums 2023 – Expert Advice Based on Skin Type

Struggling with dull skin, large pores, and breakouts? Feeling overwhelmed by all the environmental damage that affects your skin? 

Antioxidant serums can be your savior whether you have dry, oil, combination, sensitive or mature skin — they are for all skin types!

You can experience brighter, hydrated, radiant-looking skin with the right antioxidant serum and solve stubborn skin issues like hyperpigmentation, premature aging, acne, and scars. 

Most skincare brands produce and sell antioxidant-filled formulas to help people feel beautiful and healthy. Still, some fail to provide a high-quality solution for unstable compounds like vitamin C, for example.

With meticulous researchexperience, and lab engineering, we curated a list of the ten best skin recovery antioxidant serums with retinol, niacinamide, ferulic acid, AHAs and BHAs, and other active ingredients that feed the skin and keep it looking young and firm. 

Before diving into the list, here’s what you’ll learn:

  • What to look for when shopping for the antioxidant serum?
  • How and when to apply antioxidant serums
  • How to pick antioxidants based on your skin type
  • Active ingredients for each top antioxidant serum
  • Retail price
  • Each product's skin type and concern
  • Advantages of this product
  • Drawbacks of this antioxidant serum
  • What to avoid 

For busy people, here’s a TL;DR:

  1. Best anti-aging for all skin types — Revoderm Illuminous Antioxidant Serum
  2. Best for combination and oily skin — Drunk Elephant TLC Night Serum
  3. Best for fine lines and wrinkles — SkinCeuticals C E Ferulic Acid Serum
  4. Best budget option — The Inkey List Niacinamide Serum
  5. Best for sensitive skin — Anthelios AOX Antioxidant Serum
  6. Best for skin protection — Avène's A-Oxitive Antioxidant Defense Serum
  7. Best for sun damage protection — Paula's Choice Antioxidant Serum
  8. Best stable vitamin C — True Botanicals Antioxidant Booster
  9. Best serum with retinol — Dr. Lara Devgan's Antioxidant Serum
  10.  Best for uneven tone and redness — Revision Skincare C+ Correcting Complex

What to look for when shopping for the antioxidant serum?

When shopping for an antioxidant serum for your skin, quality matters more than price.

You're not just paying for the antioxidant in a bottle; you're paying for the research, ingredients, formula, and packaging that preserves the antioxidants' stability.

Packaging that keeps out UV light and the air is essential with serums because light and pH can influence the stability and longevity of antioxidants like Beta Hydroxy Acids (BHA's) and Vitamin C.

Salicylic acid is from this group of antioxidants, primarily in acne treatment products. 

Depending on your skin type, a particular blend of active ingredients can make or break your skin hence the importance of research based on your skin concerns. 

The science behind antioxidants

Antioxidants slow down skin and cell damage. They can be natural (found in fruits, vegetables, and supplements in the form of vitamins and minerals) or synthetic (made in labs).

In skincare, antioxidants prevent oxidative stress caused by free radicals (pollution, UVB/UVA lights, blue lights, etc.) and keep skin healthy. 

Not all antioxidants work the same, but each helps reach your skin goals in some way: they prevent premature aging and hyperpigmentation while renewing skin elasticity and firmness.

Antioxidants grab onto the free radicals and prevent damage to the skin before happens, soaking up harmful particles from the atmosphere. 

Many people have reported that antioxidants in skin serums prevent damage from inflammation or high skin sensitivity, which is why they work exceptionally well with SPF and sun protection products.    

How and when to apply antioxidant serums for maximum benefit?

Antioxidant serums work best when applied on a clean face before moisturizing

For example, after cleansing the face with the Detox Facial Cleanser, gently apply 5-6 drops of Illuminous Antioxidant Serum by tapping the skin lightly.

Apply skin serums in the morning and the evening, combined with an SPF moisturizer in the daytime and a rich nutrient cream for the night. 

Serums are highly beneficial to the skin of the neck and decollete, so apply them on those areas too. 

How to determine which antioxidant serum is the right for your skin type?

If you have dry skin: 

Avoid using Alpha-Hydroxy Acids (AHAs) excessively, especially on chapped or open skin. AHAs are safe for all skin types, but you should look for gentle serums with lower concentrations of abrasive ingredients like AHAs and retinol.

Dry skin allows a generous use of skincare formulas enriched with hyaluronic acid, vitamin E, and ceramides because they deeply hydrate the skin, keeping its barrier safe. 

The best antioxidant serums for dry skin contain a blend of these active ingredients.

If you have oily skin:

Serums containing vitamin C and ferulic acid have anti-inflammatory properties that reduce oil production and balance skin conditions. Since Vitamin C helps to even tone and texture, it's considered great for anti-aging. 

Ferulic acid acts as a stabilizer for both vitamins C & E — amplifying their power — while also protecting against further damage. 

If you have sensitive skin:

Moderation with products is vital, but so is the combination of antioxidants. Light use of vitamin C in combination with vitamin E can brighten and even out skin tones without irritation.

Any active ingredient with anti-inflammatory properties will work well on sensitive skin, but strong acids should be avoided or used seldom 

Sensitive skin types should always perform a patch test before using facial serums. 

If you have acne-prone skin:

Applying AHA's and BHA's will exfoliate and brighten the skin, so it's necessary to apply SPF after a serum with these ingredients for maximum results. 

Acids make the skin slightly sensitive, and SPF can prevent dark acne scars

Niacinamide stops sebum production, which could prevent new acne and clean out the pores. It works exceptionally well in a combination of active ingredients with retinol or hyaluronic acid.

If you have combination skin:

Best antioxidants serums for combination skin have active ingredients that exfoliate the skin and reduce inflammation. They often contain AHAs, niacinamide, and retinol to protect the skin.

A combination of ferulic acid and resveratrol can significantly reduce dark spots due to their skin-smoothing properties.

If you have normal skin:

Most antioxidants will positively affect your skin. But, skin can get oversaturated with products, so look out to switch up skincare when that happens (usually every few months).

Skin-balancing super antioxidant serums packed with niacinamide (vitamin B3) work amazingly well on normal skin types as they enhance its elasticity, keeping it bright and healthy. 

Vitamins A, C, and E keep the skin on the face looking young and fresh.  

A lot goes into creating potent antioxidant serums, and the following ten brands have done their homework to create a supreme product to restore, nurture and rejuvenate the skin.

Antioxidant serum #1: Revoderm Illuminous Antioxidant Serum 

Active ingredients: resveratrol, retinol palmitate, collagen-boosting copper tripeptide, niacinamide (Vitamin B-3), tocopherol (Vitamin E); 

Skin type: all skin types

Skincare concerns: acne, dark spots, eczema, dermatitis, rosacea

Pros: instantly brightens and illuminates skin; minimizes the effects of oxidative stress 

Cons: causes burning sensation to people with very sensitive skin

Price: $195.00

The Revoderm Illuminous Antioxidant Serum is exceptional for dark spots, and acne scars — the high potency of resveratrol almost instantly renews and replenishes skin after continuous use. It is fast-absorbing and gives the skin a pleasant tingle. 

It also acts fast due to the same natural compound resveratrol — reducing inflammation, improving free radical immunity, and protecting the skin from environmental toxins in record time.

Revoderm's glowy antioxidant serum has remarkable anti-aging properties

A great blend of antioxidants protects skin cells from harmful free radicals leading to premature aging and other skin issues.  

The Revoderm’s daily skin serum helps hydrate dry skin due to Vitamin B-3 in niacinamide, keeping it glowy with improved skin texture. 

Continuous use minimizes pores, so this serum is especially effective for acne-prone skin or combination skin with an oily T-zone.

Antioxidant serum #2: Drunk Elephant T.L.C. Framboos Glycolic Resurfacing Night Serum

Active ingredients: AHA, cactus extract, salicylic acid (BHA), raspberry fruit extract;

Skin type: normal, oily, combination

Skincare concerns: breakouts 

Pros: gives skin a youthful-looking glow

Cons: potent AHA/BHA blend can cause irritation

Price: $134.00

Drunk Elephant TLC Night Serum is the perfect serum for anyone looking to give their skin an extra boost of radiance. Since it is a night serum, it brightens, renews, and restores skin complexion without irritation or over-drying. 

It's great for oily skin and a potent antioxidant serum for combination skin. While AHAs work on the skin's surface to remove dead cells and speed up cell renewal for a more radiant, even tone, BHAs penetrate the pore walls for more thorough exfoliation, reducing the look of clogged pores and improving the skin's clarity. 

The raspberry extracts soothe skin while fighting free radical damage.

Antioxidant serum #3: SkinCeuticals C E Ferulic, Silymarin CF & Phloretin CF Serum    

Vitamin C Serum for Fine Lines and Wrinkles | SkinCeuticals


Active ingredients: 15% L-ascorbic acid (vitamin C), 1% alpha-tocopherol (pure vitamin E), and 0.5% ferulic acid

Skin type: dry, normal, combination, sensitive, oily

Skincare concerns: sensitized, dehydration, discoloration, aging

Pros: minimizes the appearance of fine lines and wrinkles

Cons: chemical smell, drys out the skin

Price: $169.00

SkinCeuticals C E Ferulic antioxidant serum is a multi-use product made to boost the skin barrier, protect it from damage caused by the environment, and make the skin look brighter. 

Three key ingredients – vitamin C, vitamin E, and ferulic acid work together synergistically to protect the skin from oxidative damage caused by UVA/UVB radiation, reduce inflammation, and improve discoloration. 


Silymarin CF | Blemish + Age Defense | SkinCeuticals

Silymarin CF active ingredients: 15% L-ascorbic acid (vitamin C), 0.5% silymarin, 0.5% ferulic acid, 0.5% salicylic acid

Blemish + Age Defense active ingredients: 2% dioic acid, 0.3% LHA, 1.5% salicylic acid, 3.5% glycolic acid, 0.5% citric acid 

Skin type: combination, oily

Skincare concerns: acne, aging

Pros: reduces oiliness, refines skin texture, improves skin clarity and fine lines

Cons: chemical smell

Price: $265

This dual product by SkinCeuticals is clinically proven to reduce blemishes by 36%. It works well in combination with hyaluronic acid, retinol, and SPF. 

The fusion of vitamin C and salicylic acid serums creates the best antioxidant serum for oily skin - it reduces acne and clogged pores but works wonders for aging skin. SkinCeuticals' serum duo improves skin tones, fines line, and wrinkles.

Phloretin CF Vitamin C Antioxidant Serum for Discolouration 30ml

Active ingredients: 2% phloretin, 15% L-ascorbic acid (vitamin C), 0.5% ferulic acid

Skin type: normal, oily, and combination

Skincare concerns: premature aging (free radicals from UVA/UVB, infrared radiation, and ozone pollution)

Pros: protection against atmospheric skin aging

Cons: chemical smell

Price: $150

SkinCeuticals' synergy of antioxidants improves the appearance of discoloration, fine lines, and uneven skin tone when used regularly. It contains no parabens, dyes, or artificial fragrances. 

Antioxidant serum #4: The Inkey List Niacinamide Serum

Active ingredients: 10% niacinamide, 1% hyaluronic acid, citric acid

Skin type: all skin types

Skincare concerns: excess oil production, redness, large pores

Pros: affordable, pregnancy-safe

Cons: it doesn't work for some people

Price: $9.99

The Inkey List Niacinamide Serum is a lightweight, fast-absorbing facial serum formulated to help improve skin texture, enlarged pores, and dullness. 

Active niacinamide (vitamin B-3) in The Inkey List serum is the antioxidant doing the legwork: it controls excess oil, combats blemishes, and prevents redness, while hyaluronic acid moisturizes the skin.  

The product is a customer favorite due to its affordable pricing. It has a gooey formula, and it's fragrance-free. 

It feels like a hug to the skin and layers well under moisturizers. But only apply a small amount of the product to the skin because it can get chalky if applied too thick.

Antioxidant serum #5: La Roche-Posay Anthelios AOX Daily Antioxidant Face Serum SPF 50

Active ingredients: baicalin, vitamin C, vitamin E, dimethicone, thermal spring water

Skin type: all skin types

Skincare concerns: photo-protection, sun damage, sensitive skin, wrinkles, fine lines, radiance, dark spots

Pros: has SPF 50 protection, improves fine lines, dark spots, and skin texture, allergy-tested

Cons: sunscreen smell, doesn't have a standard serum feel

Price: $42.99

Anthelios AOX Antioxidant Serum is a silky, lightweight product with quick absorption. Even though people have reported that they don't like the sunscreen smell of the product, the serum doesn't suffocate the skin as some SPF lotions do.

It is a weightless-feel serum and can be worn alone, with a moisturizer, or under makeup due to its potent antioxidant complex of baicalin, vitamin C, and E.   

Like most La Roche products, Anthelios AOX is one of the best antioxidant serums for sensitive skin because it has vitamin E, which feeds and nourishes the epidermis.

Antioxidant serum #6: Eau Thermale Avène A-Oxitive Antioxidant Defense Serum

Active ingredients: pre-tocopheryl (vitamin E), ascorbyl glucoside (vitamin C), hyaluronic acid, GP4G, thermal spring water

Skin type: all skin types

Skincare concerns: sensitivity, dehydration 

Pros: shields, boosts, and hydrates the skin, gentle product 

Cons: not fragrance-free

Price: $46.00

Avène's A-Oxitive Antioxidant Defense Serum is a fast-absorbing, lightweight but potent antioxidant serum that helps protect the skin against visible signs of aging produced by free radicals in the environment. 

It was noticeably plumping the skin when used daily, both day and night. Skin appears reduced in pores, fine lines, and wrinkles with the Avène antioxidant serum.

Vitamin E protects from free radicals, and vitamin C works toward a more radiant complexion. 

Antioxidant serum #7: Paula's Choice RESIST Super Antioxidant Serum


Active ingredients: ferulic acid, tocotrienols, THD (a highly stable form of vitamin C), peptides, magnesium ascorbyl phosphate (a stable, hydrating form of vitamin C), green tea extract, Curcuma longa root

Skin type: all skin types

Skincare concerns: premature aging, sun-damaged skin, dullness

Pros: easy to apply, skin is noticeably younger after regular use, stable vitamin C

Cons: some people have a bad reaction to the product

Price: $43.00

Paula's Choice Antioxidant Serum has great creamy consistency - it's very easy to apply. With six different antioxidants that create a delightful blend of benefits, this serum stands out for its skin renewal and sun damage protection properties.

This is a remarkable product because it has loads of stable vitamin C, which is very difficult to achieve in cosmetics production. 

Use it twice a day after cleansing, toning, and exfoliating. Apply moisturizer after the RESIST Super Antioxidant Serum for a full day of hydrated and plump skin.

Antioxidant serum #8: True Botanicals Antioxidant Booster

Active ingredients: vitamin C, ferulic acid

Skin type: all skin types

Skincare concerns: dark spots, dullness, anti-aging, wrinkles

Pros: unique formulation, high potency, powder form makes it longer-lasting

Cons: not practical for traveling, can require more products for application

Price: $90.00 

Even though it isn't a serum per se, Topical Vitamin C Booster Powder works exceptionally well for all skin types because it is in powder form. 

If this sounds odd, you may find it interesting how vitamin C is most stable in powder form. Besides, this antioxidant starts to degrade when exposed to liquid - so keeping it in an air-tight, light-safe container in powder makes it long-lasting and worth the hefty price.

Due to a combination of vitamin C and ferulic acid in this product, you witness dramatic brightening results when you mix one to two shakes of the Vitamin C Booster with your favorite serum, cream, or moisturizer. 

Use it for all parts that show signs of aging - face, neck, décolleté, hands. 

Antioxidant serum #9: Lara Devgan Scientific Beauty Retinol + Bakuchiol Serum 2.5x

Active ingredients: retinol, bakuchiol, licorice root extract, black leaf extract

Skin type: normal, dry, combination, and oily

Skincare concerns: anti-aging, dark spots, dullness, pores, fine lines

Pros: a blend of antioxidants retinol and bakuchiol works together superb

Cons: avoid if pregnant or breastfeeding, a hefty price

Price: $300.00

Dr. Lara Devgan's antioxidant serum pairs well with ferulic and hyaluronic acids and vitamins C, B, and E. 

The active ingredient retinol is the gold standard for reducing fine lines, wrinkles, and other indications of aging. A perfect mix with bakuchiol combats fine wrinkles, hyperpigmentation, and enlarged pores.

It's NOT the best antioxidant serum for sensitive skin. To avoid irritating sensitive skin with retinol, try using the product every other day or every third day at first, and work up from there.

Antioxidant serum #10: Revision Skincare C+ Correcting Complex 30%

Active ingredients: THD (vitamin C), tocopheryl acetate (vitamin E), ubiquinone (coenzyme Q10)

Skin type: all, but ideal for dry, oily, or combination

Skincare concerns: sun damage, redness, fine lines

Pros: supports skin's natural production of vitamins C and E, makes skin glowy


Price: $170.00

C+ Correcting Complex 30%® 1 fl oz supports long-term skin health, illuminates, refines, and rejuvenates the skin of the face, neck, and hands and décolleté. 

Apply one product pump on the face, spreading it evenly on wanted areas. You can apply another pump on the neck and chest. 

Are there any popular antioxidant serums that you should avoid, and why? 

When shopping for antioxidant serums, it's essential to do your research and make sure you're getting the most effective ingredients for your skin type. Some active ingredients from plants may not be as effective or safe as other forms, so always check the ingredients list before you buy. 

Find what works for you and get an antioxidant serum that suits your skin's needs! 

Retinol is commonly used in serums, a vitamin A derivative touted as an effective anti-aging agent. However, it can irritate some people's skin, and overuse may cause irritation and sensitization. 

When used in high concentrations, vitamin C can cause mild stinging or burning sensations and increase sun sensitivity. You should use a daily SPF when using this type of serum. 

Overusing alpha hydroxy acids (AHAs) could result in dryness, irritation, redness, and burning sensations. AHAs can also make your skin more prone to sunburns due to their exfoliating properties. Usually not the best antioxidant serum for sensitive skin.

Synthetic fragrances often found in many skincare products may irritate sensitive skin types or trigger allergies in some people. If you notice any irritation from these ingredients, look for fragrance-free alternatives. 

Who are we, and why should you trust us? 

Revoderm Pharma was founded by a triple-certified dermatologist, dermatopathologist, and laboratory medicine specialist Dr. Ken Alanen and skincare and medical cosmetic specialist, Ildiko Juhasz, with 20+ years of clinical experience. 

Together, they have created a unique fusion of clinical dermatology and laboratory medicine — a medical-grade luxury skincare line — ensuring that our products are backed by solid scientific research. 

Revoderm Pharma has been trusted by patients and clients at, a leading dermatology and laser cosmetic practice, for over a decade. Our products are not only tested, but have consistently delivered real results in clinical settings, giving you peace of mind knowing that a proven track record backs your skincare.