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Voted NewBeauty's Favorite Serum for Sensitive Skin, 2026 — Shop now →

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Barrier support

Prebiotics

Also known as Skin microbiome support

Ingredients that nourish the good microbes living on your skin, helping keep the skin surface balanced, comfortable and resilient.

Revoderm products with Prebiotics

What are prebiotics?

Your skin is home to a community of microorganisms, often called the skin microbiome. Prebiotics are ingredients that feed the helpful members of that community. They are different from probiotics, which are the microbes themselves. In skincare, prebiotics help keep the skin surface in balance so it can do its job of holding in moisture and keeping irritants out.

What they do for your skin

  • Support a balanced, healthy-looking skin surface
  • Help skin feel calmer and more comfortable
  • Support the skin barrier, especially when it is stressed by weather or strong actives
  • Work alongside hydrators to keep skin feeling soft

How to use them

Our HA + Prebiotics Serum uses glycerin and aloe leaf juice as prebiotics, together with hyaluronic acid for hydration. Apply a few drops to clean, slightly damp skin morning and night, then follow with moisturizer and, in the morning, sunscreen.

Who they're for

Every skin type can benefit. Prebiotics are especially helpful for sensitive or reactive skin and for anyone using retinol or acne treatments that can leave skin feeling dry or tight.

Common questions

What is the difference between prebiotics and probiotics?
Prebiotics feed the helpful microbes on your skin. Probiotics are the microbes themselves.
Can I use prebiotics with retinol or acids?
Yes. Prebiotic skincare is gentle and helps keep skin comfortable while you use stronger actives.
Are prebiotics good for acne-prone skin?
Yes. A balanced, well-hydrated skin surface is a good base for any acne routine.

This guide is general skincare information, not medical advice. If you're pregnant, nursing, using prescription skincare or have a skin condition, check with your doctor or our clinic team first.

Not sure what your skin needs?

Take our skin quiz for a routine matched to your skin, or book a free consult with our skin experts.